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1:  P03198Reports  DNA polymerase...[gi:118858] BLink, Conserved Domains, Links
LOCUS       P03198                  1015 aa            linear   VRL 01-MAY-2007
DEFINITION  DNA polymerase.
ACCESSION   P03198
VERSION     P03198  GI:118858
DBSOURCE    swissprot: locus DPOL_EBV, accession P03198;
            class: standard.
            created: Jul 21, 1986.
            sequence updated: Jul 21, 1986.
            annotation updated: May 1, 2007.
            xrefs: V01555.2, CAA24805.1, DJBE2L, 1H15C, 1H15F
            xrefs (non-sequence databases): LinkHub:P03198, InterPro:IPR006172,
            InterPro:IPR006133, InterPro:IPR006134, InterPro:IPR012337,
            Gene3D:G3DSA:3.30.420.10, PANTHER:PTHR10322, Pfam:PF00136,
            Pfam:PF03104, PRINTS:PR00106, SMART:SM00486, PROSITE:PS00116
KEYWORDS    3D-structure; DNA replication; DNA-binding; DNA-directed DNA
            polymerase; Early protein; Nuclear protein; Nucleotidyltransferase;
            Transferase.
SOURCE      Human herpesvirus 4 (strain B95-8) (Epstein-Barr virus (strain
            B95-8))
  ORGANISM  Human herpesvirus 4 (strain B95-8)
            Viruses; dsDNA viruses, no RNA stage; Herpesviridae;
            Gammaherpesvirinae; Lymphocryptovirus.
REFERENCE   1  (residues 1 to 1015)
  AUTHORS   Bankier,A.T., Deininger,P.L., Farrell,P.J. and Barrell,B.G.
  TITLE     Sequence analysis of the 17,166 base-pair EcoRI fragment C of B95-8
            Epstein-Barr virus
  JOURNAL   Mol. Biol. Med. 1 (1), 21-45 (1983)
   PUBMED   6092825
  REMARK    NUCLEOTIDE SEQUENCE [GENOMIC DNA].
REFERENCE   2  (residues 1 to 1015)
  AUTHORS   Baer,R., Bankier,A.T., Biggin,M.D., Deininger,P.L., Farrell,P.J.,
            Gibson,T.J., Hatfull,G., Hudson,G.S., Satchwell,S.C., Seguin,C.,
            Tuffnell,P.S. and Barrell,B.G.
  TITLE     DNA sequence and expression of the B95-8 Epstein-Barr virus genome
  JOURNAL   Nature 310 (5974), 207-211 (1984)
   PUBMED   6087149
  REMARK    NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
COMMENT     On Oct 25, 2005 this sequence version replaced gi:67032.
            [CATALYTIC ACTIVITY] Deoxynucleoside triphosphate + DNA(n) =
            diphosphate + DNA(n+1).
            [SUBCELLULAR LOCATION] Nucleus.
            [SIMILARITY] Belongs to the DNA polymerase type-B family.
FEATURES             Location/Qualifiers
     source          1..1015
                     /organism="Human herpesvirus 4 (strain B95-8)"
                     /specific_host="Homo sapiens (Human)"
                     /db_xref="taxon:10377"
     gene            1..1015
                     /locus_tag="BALF5"
     Protein         1..1015
                     /locus_tag="BALF5"
                     /product="DNA polymerase"
                     /EC_number="2.7.7.7"
     Region          1..1015
                     /locus_tag="BALF5"
                     /region_name="Mature chain"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="DNA polymerase. /FTId=PRO_0000046505."
     Region          136..>163
                     /locus_tag="BALF5"
                     /region_name="DNA_pol_B_exo"
                     /note="DNA polymerase family B, exonuclease domain. This
                     domain has 3' to 5' exonuclease activity and adopts a
                     ribonuclease H type fold; pfam03104"
                     /db_xref="CDD:66758"
     Region          288..797
                     /locus_tag="BALF5"
                     /region_name="POLBc"
                     /note="DNA polymerase type-B family; DNA directed DNA
                     polymerase. Posseses DNA binding, polymerase and 3'-5'
                     exonuclease activity; cd00145"
                     /db_xref="CDD:29064"
     Region          288..765
                     /locus_tag="BALF5"
                     /region_name="POLBc"
                     /note="DNA polymerase type-B family; DNA polymerase alpha,
                     delta, epsilon and zeta chain (eukaryota), DNA polymerases
                     in archaea, DNA polymerase II in e; smart00486"
                     /db_xref="CDD:47792"
     Region          532..1013
                     /locus_tag="BALF5"
                     /region_name="DNA_pol_B"
                     /note="DNA polymerase family B. This region of DNA
                     polymerase B appears to consist of more than one
                     structural domain, possibly including elongation,
                     DNA-binding and dNTP binding activities; pfam00136"
                     /db_xref="CDD:64022"
     Region          629..630
                     /locus_tag="BALF5"
                     /region_name="Beta-strand region"
                     /experiment="experimental evidence, no additional details
                     recorded"
ORIGIN      
        1 msgglfynpf lrpnkgllkk pdkeylrlip kcfqtpgaag vvdvrgpqpp lcfyqdsltv
       61 vggdedgkgm wwrqraqegt arpeadthgs pldfhvydil etvythekca vipsdkqgyv
      121 vpcgivikll grrkadgasv cvnvfgqqay fyasapqgld vefavlsalk astfdrrtpc
      181 rvsvekvtrr simgygnhag dyhkitlshp nsvchvatwl qdkhgcrife anvdatrrfv
      241 ldndfvtfgw yscrraiprl qhrdsyaele ydcevgdlsv rredsswpsy qalafdiecl
      301 geegfptatn eadlilqisc vlwstgeeag ryrrilltlg tcediegvev yefpseldml
      361 yaffqlirdl sveivtgynv anfdwpyild rarhiysinp aslgkiragg vcevrrphda
      421 gkgflrantk vritglipid myavcrdkls lsdykldtva rhllgakked vhykeiprlf
      481 aagpegrrrl gmycvqdsal vmdllnhfvi hvevaeiaki ahipcrrvld dgqqirvfsc
      541 llaaaqkenf ilpmpsasdr dgyqgatviq plsgfynspv lvvdfaslyp siiqahnlcy
      601 stmitpgeeh rlaglrpged yesfrltggv yhfvkkhvhe sflaslltsw lakrkaikkl
      661 laacedprqr tildkqqlai kctcnavygf tgvanglfpc lsiaetvtlq grtmleraka
      721 fvealspanl qalapspdaw aplnpegqlr viygdtdslf iecrgfsese tlrfadalaa
      781 httrslfvap isleaektfs clmlitkkry vgvltdgktl mkgvelvrkt ackfvqtrcr
      841 rvldlvlada rvkeaaslls hrpfqesftq glpvgflpvi dilnqaytdl regrvpmgel
      901 cfstelsrkl saykstqmph lavyqkfver neelpqihdr iqyvfvepkg gvkgarktem
      961 aedpayaerh gvpvavdhyf dkllqgaani lqclfdnnsg aalsvlqnft arppf
//

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