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1:  P09252Reports  DNA polymerase...[gi:118893] BLink, Conserved Domains, Links
LOCUS       P09252                  1194 aa            linear   VRL 01-MAY-2007
DEFINITION  DNA polymerase.
ACCESSION   P09252
VERSION     P09252  GI:118893
DBSOURCE    swissprot: locus DPOL_VZVD, accession P09252;
            class: standard.
            created: Jul 1, 1989.
            sequence updated: Jul 1, 1989.
            annotation updated: May 1, 2007.
            xrefs: X04370.1, CAA27911.1, DJBE28
            xrefs (non-sequence databases): DrugBank:APRD00567,
            DrugBank:APRD00600, InterPro:IPR006172, InterPro:IPR006133,
            InterPro:IPR006134, InterPro:IPR012337, Gene3D:G3DSA:3.30.420.10,
            PANTHER:PTHR10322, Pfam:PF00136, Pfam:PF03104, PRINTS:PR00106,
            SMART:SM00486, PROSITE:PS00116
KEYWORDS    DNA replication; DNA-binding; DNA-directed DNA polymerase; Nuclear
            protein; Nucleotidyltransferase; Transferase.
SOURCE      Human herpesvirus 3 (strain Dumas)
  ORGANISM  Human herpesvirus 3 (strain Dumas)
            Viruses; dsDNA viruses, no RNA stage; Herpesviridae;
            Alphaherpesvirinae; Varicellovirus.
REFERENCE   1  (residues 1 to 1194)
  AUTHORS   Davison,A.J. and Scott,J.E.
  TITLE     The complete DNA sequence of varicella-zoster virus
  JOURNAL   J. Gen. Virol. 67 (PT 9), 1759-1816 (1986)
   PUBMED   3018124
  REMARK    NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
COMMENT     On Jun 10, 2005 this sequence version replaced gi:67040.
            [CATALYTIC ACTIVITY] Deoxynucleoside triphosphate + DNA(n) =
            diphosphate + DNA(n+1).
            [SUBCELLULAR LOCATION] Nucleus.
            [SIMILARITY] Belongs to the DNA polymerase type-B family.
FEATURES             Location/Qualifiers
     source          1..1194
                     /organism="Human herpesvirus 3 (strain Dumas)"
                     /specific_host="Homo sapiens (Human)"
                     /db_xref="taxon:10338"
     gene            1..1194
                     /gene="28"
     Protein         1..1194
                     /gene="28"
                     /product="DNA polymerase"
                     /EC_number="2.7.7.7"
     Region          1..1194
                     /gene="28"
                     /region_name="Mature chain"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="DNA polymerase. /FTId=PRO_0000046525."
     Region          341..892
                     /gene="28"
                     /region_name="POLBc"
                     /note="DNA polymerase type-B family; DNA directed DNA
                     polymerase. Posseses DNA binding, polymerase and 3'-5'
                     exonuclease activity; cd00145"
                     /db_xref="CDD:29064"
     Region          597..1136
                     /gene="28"
                     /region_name="DNA_pol_B"
                     /note="DNA polymerase family B. This region of DNA
                     polymerase B appears to consist of more than one
                     structural domain, possibly including elongation,
                     DNA-binding and dNTP binding activities; pfam00136"
                     /db_xref="CDD:64022"
ORIGIN      
        1 mairtgfcnp fltqasgiky nprtgrgsnr eflhsykttm ssfqflapkc ldedvpmeer
       61 kgvhvgtlsr ppkvycngke vpildfrcss pwprrvniwg eidfrgdkfd prfntfhvyd
      121 ivetteaasn gdvsrfatat rplgtvitll gmsrcgkrva vhvygicqyf yinkaevdta
      181 cgirsgsels vllaeclrss mitqndatln gdknafhgts fksaspesfr veviertdvy
      241 yydtqpcafy rvyspsskft nylcdnfhpe lkkyegrvda ttrflmdnpg fvsfgwyqlk
      301 pgvdgervrv rpasrqltls dveidcmsdn lqaipnddsw pdykllcfdi ecksggsnel
      361 afpdathled lviqisclly siprqslehi llfslgscdl pqryvqemkd aglpeptvle
      421 fdsefellia fmtlvkqyap efatgynivn fdwafimekl nsiyslkldg ygsinrgglf
      481 kiwdvgksgf qrrskvking lisldmyaia teklklssyk ldsvarealn eskrdlpykd
      541 ipgyyasgpn trgiigeyci qdsalvgklf fkylphlels avarlaritl tkaiydgqqv
      601 riytcllgla ssrgfilpdg gypatfeykd vipdvgdvee emdedesvsp tgtssgrnvg
      661 ykgarvfdpd tgfyidpvvv ldfaslypsi iqahnlcftt ltlnfetvkr lnpsdyatft
      721 vggkrlffvr snvresllgv llkdwlamrk airaripgss sdeavlldkq qaaikvvcns
      781 vygftgvaqg flpclyvaat vttigrqmll strdyihnnw aaferfitaf pdiessvlsq
      841 kayevkviyg dtdsvfirfk gvsvegiaki gekmahiist alfcppikle cektfiklll
      901 itkkkyigvi yggkvlmkgv dlvrknncqf indyarklve lllyddtvsr aaaeascvsi
      961 aewnrramps gmagfgriia dahrqitspk ldinkfvmta elsrppsayi nrrlahltvy
     1021 yklvmrqgqi pnvreripyv ivaptdevea daksvallrg dplqntagkr cgeakrklii
     1081 sdlaedpihv tshglslnid yyfshligta svtfkalfgn dtklterllk rfipetrvvn
     1141 vkmlnrlqaa gfvcihapcw dnkmnteaei teeeqshqim rrvfcipkai lhqs
//

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