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1:  P07918Reports  DNA polymerase...[gi:118882] BLink, Conserved Domains, Links
LOCUS       P07918                  1240 aa            linear   VRL 01-MAY-2007
DEFINITION  DNA polymerase.
ACCESSION   P07918
VERSION     P07918  GI:118882
DBSOURCE    swissprot: locus DPOL_HHV21, accession P07918;
            class: standard.
            created: Aug 1, 1988.
            sequence updated: Aug 1, 1988.
            annotation updated: May 1, 2007.
            xrefs: M16321.1, AAA45853.1, DJBE21
            xrefs (non-sequence databases): InterPro:IPR006172,
            InterPro:IPR006133, InterPro:IPR006134, InterPro:IPR012337,
            Gene3D:G3DSA:3.30.420.10, PANTHER:PTHR10322, Pfam:PF00136,
            Pfam:PF03104, PRINTS:PR00106, SMART:SM00486, PROSITE:PS00116
KEYWORDS    DNA replication; DNA-binding; DNA-directed DNA polymerase; Nuclear
            protein; Nucleotidyltransferase; Transferase.
SOURCE      Human herpesvirus 2 strain 186
  ORGANISM  Human herpesvirus 2 strain 186
            Viruses; dsDNA viruses, no RNA stage; Herpesviridae;
            Alphaherpesvirinae; Simplexvirus.
REFERENCE   1  (residues 1 to 1240)
  AUTHORS   Tsurumi,T., Maeno,K. and Nishiyama,Y.
  TITLE     Nucleotide sequence of the DNA polymerase gene of herpes simplex
            virus type 2 and comparison with the type 1 counterpart
  JOURNAL   Gene 52 (2-3), 129-137 (1987)
   PUBMED   3038677
  REMARK    NUCLEOTIDE SEQUENCE [GENOMIC DNA].
COMMENT     On Jul 5, 2005 this sequence version replaced gi:67039.
            [CATALYTIC ACTIVITY] Deoxynucleoside triphosphate + DNA(n) =
            diphosphate + DNA(n+1).
            [SUBCELLULAR LOCATION] Nucleus.
            [SIMILARITY] Belongs to the DNA polymerase type-B family.
FEATURES             Location/Qualifiers
     source          1..1240
                     /organism="Human herpesvirus 2 strain 186"
                     /specific_host="Homo sapiens (Human)"
                     /db_xref="taxon:10312"
     Protein         1..1240
                     /product="DNA polymerase"
                     /EC_number="2.7.7.7"
     Region          1..1240
                     /region_name="Mature chain"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="DNA polymerase. /FTId=PRO_0000046515."
     Region          361..933
                     /region_name="POLBc"
                     /note="DNA polymerase type-B family; DNA directed DNA
                     polymerase. Posseses DNA binding, polymerase and 3'-5'
                     exonuclease activity; cd00145"
                     /db_xref="CDD:29064"
     Region          617..1200
                     /region_name="DNA_pol_B"
                     /note="DNA polymerase family B. This region of DNA
                     polymerase B appears to consist of more than one
                     structural domain, possibly including elongation,
                     DNA-binding and dNTP binding activities; pfam00136"
                     /db_xref="CDD:64022"
ORIGIN      
        1 mfcaaggpas pggksaaraa sgffaphnpr gatqtapppc rrqnfynphl aqtgtqpkap
       61 gpaqrhtyys ecdefrfiap rsldedapae qrtgvhdgrl rrapkvycgg derdvlrvgp
      121 egfwprrlrl wggadhapeg fdptvtvfhv ydilehveha ysmraaqlhe rfmdaitpag
      181 tvitllgltp eghrvavhvy gtrqyfymnk aevdrhlqcr aprdlcerla aalrespgas
      241 frgisadhfe aevveradvy yyetrptlyy rvfvrsgral aylcdnfcpa irkyeggvda
      301 ttrfildnpg fvtfgwyrlk pgrgnapaqp rpptafgtss dvefnctadn lavegamcdl
      361 payklmcfdi eckaggedel afpvaerped lviqisclly dlsttalehi llfslgscdl
      421 peshlsdlas rglpapvvle fdsefemlla fmtfvkqygp efvtgyniin fdwpfvltkl
      481 teiykvpldg ygrmngrgvf rvwdigqshf qkrskikvng mvnidmygii tdkvklssyk
      541 lnavaeavlk dkkkdlsyrd ipayyasgpa qrgvigeycv qdsllvgqlf fkflphlels
      601 avarlagini trtiydgqqi rvftcllrla gqkgfilpdt qgrfrgldke apkrpavprg
      661 egerpgdgng dedkdddedg dedgdereev aretggrhvg yqgarvldpt sgfhvdpvvv
      721 fdfaslypsi iqahnlcfst lslrpeavah leadrdylei evggrrlffv kahvreslls
      781 illrdwlamr kqirsripqs ppeeavlldk qqaaikvvcn svygftgvqh gllpclhvaa
      841 tvttigreml latrayvhar waefdqllad fpeaagmrap gpysmriiyg dtdsifvlcr
      901 gltgealvam gdkmashisr alflppikle cektftklll iakkkyigvi cggkmlikgv
      961 dlvrknncaf inrtsralvd llfyddtvsg aaaalaerpa eewlarplpe glqafgavlv
     1021 dahrritdpe rdiqdfvlta elsrhprayt nkrlahltvy yklmarraqv psikdripyv
     1081 ivaqtrevee tvarlaalre ldaaapgdep appaalpspa krpretpsha dppggaskpr
     1141 kllvselaed pgyaiargvp lntdyyfshl lgaacvtfka lfgnnakite sllkrfipet
     1201 whppddvaar lraagfgpag agataeetrr mlhrafdtla
//

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